Vitamin E Tocotrienols: ‘Insanely Great’
Vitamin E saturated analogue tocopherols have been extensively investigated (particularly alpha tocopherol), but little has been known about the unsaturated vitamin E analogues called tocotrienols.
A brilliant paper published in Biochemical Pharmacology called Tocotrienols, the vitamin E of the 21st century: Its potential against cancer and other chronic diseases is a must read for everyone interested in vitamin E science…
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Tocotrienols in Combat: Fighting the Statin Damage Crisis
When I lost my short-term memory six weeks after starting Lipitor, I immediately suspected my new medicine and discontinued the drug. At my next NASA physical, I was urged to resume taking it and reluctantly agreed, only to suffer a much worse memory loss a few weeks later. For 12 hours, I suddenly became a teenager with total recall for my high school days, but absolutely no awareness that I was a doctor, married with children and a former NASA astronaut. This began my decade of research on the subject.
To my amazement, I discovered an extraordinary lack of information in my own medical community as to the true spectrum of statin drug side effects. I started a Web site (www.spacedoc.com), which has become a major message board and resource for those with statin drug-associated side effects. My four books—Lipitor, Thief of Memory, Statin Drug Side Effects, Statin Damage Crisis and The Dark Side of Statins—present the reasons for adverse effects of statins on the human body…
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Natural Approaches to HDL, LDL and Total Cholesterol
It’s that time of year when consumers buckle down and try to reduce. They want to cut calories, frivolous spending and bad habits. In the past, one of the yearly New Year’s goals may have been to reduce all forms of cholesterol; however, this is not the case anymore as the complexity of cholesterol is continually being explored in medical journals and doctors’ offices. Research has taught us the error of thinking that “getting the numbers down” is the only cholesterol goal. Not all cholesterol is unhealthy; in fact, some even need to work to balance their levels…
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No Good News for Vitamin E
A recent meta-analysis published in the British Medical Journal (BMJ) has it that vitamin E supplements may increase the risk of severe strokes, broadly concluding that “indiscriminate widespread use of vitamin E should be cautioned against.”The study’s authors stated that though research has shown alpha-tocopherol vitamin E to be instrumental in preventing ischemic stroke, it may raise the risk of the more detrimental, though less prevalent, hemorrhagic stroke. “In terms of absolute risk,” the study said, “this translates into one additional hemorrhagic stroke for every 1,250 individuals taking vitamin E, in contrast to one ischemic stroke prevented per 476 individuals taking vitamin E…
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Regulations: The regulatory landscape for vitamin E tocotrienol
All of the tocotrienol ingredients on the market claim to be GRAS (generally recognised as safe), with the determinations being self-affirmed. American River Nutrition, which sources from annatto, said its DeltaGold branded ingredient received self-affirmed GRAS status in July 2010…
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Supply: The varied sources of vitamin E tocotrienol
The commercial extraction of tocotrienols from palm oil began in earnest in the mid 1980s, with much of the science coming out of Malaysia. This is understandable, given Malaysia was the largest palm oil producer until 2009, with about 18 million tonnes per year. The country’s top spot was usurped by Indonesia this year, which produces 21 million tonnes…
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Differentiation key to vitamin E tocotrienol success
When consumers think of vitamin E, they are probably thinking of the tocopherol form. The vitamin comes in eight forms: Four tocopherols and four tocotrienols (alpha, beta, gamma, and delta-forms of each).
John Kurstjens from Lipid Nutrition, which offers a tocotrienol ingredient from palm oil, told NutraIngredients: “Vitamin E is a mature market and companies are looking to differentiate their products in this market,” and that is where tocotrienols have potential. Tocotrienols are seen as “the next generation vitamin E”, he added…
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The science of the ‘next generation’ vitamin E
One of the earliest reports to link tocotrienols to heart health – via cholesterol reduction – was a paper by Dr Asaf Qureshi at the USDA. Writing in the Journal of Biological Chemistry (Vol. 261, pp. 10544-10550.) in 1986, Dr Qureshi and his co-workers reported that the a cereal’s ability to reduce cholesterol concentrations was directly linked to its tocotrienol concentrations, with barley and oats coming out on top, followed by rye, wheat and then corn…
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American River Nutrition Inc. DeltaGOLD Research
Delta-tocotrienol is a rapidly developing novel component of vitamin E. It is naturally derived from several sources, including palm, rice bran, and annatto, all containing various compositions of tocopherol and tocotrienol. Here we will discuss the benefits and superior function of delta-tocotrienol, including its role in cholesterol reduction and cardiovascular disease, its influence on metabolic syndrome and diabetes, and its potential in cancer and chemoprevention…
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Tocotrienol and Familial Dysautonomia
Berish Rubin starts his day like many chareidi men. He wakes up before 7 a.m., rushes off to shul to daven Shacharis, followed by a shiur, and returns home briefly before commuting to work. His cell phone is set to ring daily at 1:23 p.m., to remind him to get ready for the 1:40 p.m. Minchah. After Minchah he heads back to work. All typicality ends here, mostly due to the fact that Dr. Rubin loves his job and has a driving passion which does not allow him much time to rest. Knowing that Jewish children and families need his assistance, it is his feeling that every day makes a difference. Berish Rubin lives day in and day out with Hillel’s perspective, im lo achshav eimasai — if not now, when? …
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Delta Tocotrienol: The New Vitamin E Anti-Inflammatory Superstar
For more than a decade, I’ve been following research on delta tocotrienol, a natural compound belonging to the vitamin E family. The results have now reached what I would call the “terrific level,” and I want to encourage those of you with arterial health issues to consider adding this emerging anti-inflammatory superstar to your supplement arsenal…
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Tocotrienol Webinar on Natural Products Insider
Unknown to many, the tocotrienol subfamily of vitamin E possesses powerful properties that are not exhibited by tocopherols. A considerable fraction of today’s nutritional community assumes that vitamin E is synonymous with tocopherol. The reality is that natural vitamin E includes at least eight chemically distinct molecules, and an expanding body of evidence supports that these are functionally unique. Surprisingly, alpha-tocopherol was found to interfere with tocotrienol’s unique benefits, confirming the need for nature-sourced, tocopherol-free tocotrienol products. In this Webinar, world-expert Dr. Barrie Tan will decode the confusing and contradictory information on vitamin E, elucidating the highly active tocotrienols with emphasis on benefits of the most potent delta- and gamma-isoforms: cholesterol-reduction, cancer inhibition and mechanisms, antioxidant status, bioavailability, and eye benefits. Newest pre-clinical and clinical studies will be discussed…
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Annatto Tocotrienols, Reshaping the Vitamin E Landscape
With obesity and diabetes numbers soaring, and cardiovascular deaths ranking number one worldwide, it is clear that a shift in healthcare is necessary. The current healthcare model is a medical one, in which disease symptoms are treated late in life and the underlying issues are neglected. A model of prevention is needed, with nutraceuticals being used early in life to prevent chronic disorders. One key player in this preventive model is vitamin E…
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The Most Powerful Members of The Vitamin E Family
Delta-Tocotrienols:The Most Powerful Members of The Vitamin E Family Overlooked Until Recently, Tocotrienols Are The Other Half Of The Vitamin E…
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Vitamin E Component Dramatically More Effective at Supporting Heart Health
Vitamin E is often thought of as a single entity. However, it is a mixture of both tocotrienols and tocopherols, two forms of the same vitamin. Scientists have found that although both tocotrienols and tocopherols are similar, they work differently in the body. In fact, the newest research indicates that even though both forms possess antioxidant activity, tocotrienols are superior to tocopherols in ways essential to good health. Furthermore, evidence indicates that tocotrienols are absorbed better than tocopherols1 and that alpha-tocopherol (the most common form of Vitamin E supplementation worldwide) blocks absorption of tocotrienols,2 compromising tocotrienols’ ability to maintain healthy cholesterol levels and sustain the integrity of nerves…
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Annatto Tocotrienol Significant Role in Blood Sugar Control
The rate and prevalence of type 2 diabetes, especially in adults, is increasing at an alarming rate.1 Many factors are involved in the development of type 2 diabetes, and some have been more extensively studied than others. Recently, medical interest has turned to a pre-diabetes condition called metabolic syndrome, also called syndrome X or insulin resistance syndrome. The prevalence of metabolic syndrome, a major causative factor both in the early development of type 2 diabetes and cardiovascular disease, is becoming alarmingly widespread.2-4 According to the American Diabetes Association about 41 million people in the United States, ages 40 to 74, have pre-diabetes.5 In addition, there is the increasing prevalence of childhood obesity,6 which contributes to the subsequent development of metabolic syndrome and type 2 diabetes. Thus, there is an urgency to identify cost-effective solutions for metabolic syndrome and insulin resistance that are safe, efficacious and complimentary to current treatments…
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Tocotrienols as Anti-Chlamydials
A while back, Dr. Stratton had sent me a few articles about tocotreinols. Periodically I get a slew of articles from him frequently without explanation in the email. I kind of take it as a test; it brings me back to my grad school habits, that my job is to figure out the significance of them to this whole Cpni project. I don’t think that he is trying to test me, but rather the Cpn links are obvious to him as he is so expert in the biochemistry and microbiological details. It doesn’t always occur to him that others may lack the advanced degree to discern his train of thought! Red (Dan), who has had conversations with Dr. Stratton regarding Cpn and rosaceai, has similarly reported having conversations with the good doctor where he has missed half the information just scrambling to take notes and keep up.
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The 21st Century Vitamin E?
Vitamin E—the golden capsule, our most potent fat-soluble antioxidant—has a secret. It turns out to be a many-faceted nutritional gem, with a highly specific form called delta-tocotrienol that offers profound cholesterol-lowering properties, potent cardiovascular benefits, and in laboratory studies, verifiable anticancer effects. In new research, delta-tocotrienol proved 40 to 60-fold more powerful as a free radical scavenger than alpha-tocopherol, the most commonly available Vitamin E in supplements…
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